On point with off-label Botox
Botulinum toxin type A’s potential use in scar contracture could be particularly interesting for cosmetic surgeons, according to Dr. Torkian. Studies suggest that injecting botulinum toxin into a wound might improve the cosmetic results of wound healing and scar formation.
“It’s a little counterintuitive based on what we know about the mechanism of botulinum toxin because there’s no nerve to target or organ junction-mediated activity that occurs through scar contracture or wound healing. But somehow or another, it improves wound healing. I’m very excited to see how that develops,” Dr. Torkian says.
Researchers are experimenting with watering down botulinum toxin A to correct crepey areas of the neck.
“It requires a lot of units of botulinum toxin to get the effect that [researchers] were seeing, and it doesn’t last long enough at this point, but it’s interesting how the little dermal junction between the muscle and skin can be manipulated to improve some of the crepey lines that we didn’t think we could do anything about,” Dr. Torkian says.
Drs. Freiman, Lickstein, Torkian, Chaboki and Chasan report no relevant disclosures.